Astrocytes contribute to the ReelinApoER2 signalling pathway in the adult brain

Kirsty Malone
Reelin is 400 kDa, secreted glycoprotein that signals via the lipoprotein receptors ApoER2 and VLDLR, and the cytosolic adaptor protein Dab1 in target cells. This Reelin signalling pathway has been shown to be essential for the formation of the radial glia scaffold and subsequent layering of the cortex during neural development. Reelin's role in the adult brain has not been clearly established, however, recent studies have implicated Reelin as an obligatory component of LTP in...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.