Defining the tropism of Listeria monocytogenes using a comparative genomics approach

Sarah C McIlwham
Listeria monocytogenes is a human foodborne pathogen capable of causing invasive and non-invasive infections. Ubiquitous in the environment, strains are often classified into lineages I (serovars 1/2a, 1/2c, 3a; food); II (containing serovars 1/2b, 4b, 3b; human illness); and III (4a, 4c; food-production). It is not clearly understood how serovars become tropic to a particular niche. The objective of this project was to investigate strain differences in clinical, environmental and food isolates, with the aim...
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