Non-small cell lung cancer: Assessment of methodologies to combine survival curves in meta-analysis.

Craig. Earle
Purpose. To assess the accuracy of different methods of combining published survival curves into a summary curve that can be used in disease models or to make treatment comparisons in meta-analysis. Methods. Five methods for combining survival curves were identified: (1) iterative generalized least-squares (IGLS, Dear 94), (2) meta-analysis (MA) of failure-time data with adjustment for covariates (MFD, Hunink 94), (3) non-linear regression (NLR, Shore 90), (4) log relative risk (LRR, Voest 89), and (5)...
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