Studies on the differentiation of cranio-visceral cartilage in normal and premature death mutant embryos of Ambystoma mexicanum.

Ann C. Graveson
The self-differentiative ability of the cranial neural crest cells in the Mexican axolotl, Ambystoma mexicanum was tested at various developmental stages. The processes through which cartilage determination occurs are far from complete; only a very small number of these cultures contained cartilage, although all appeared healthy and contained melanocytes and abundant mesenchyme. At all of these stages, pharyngeal endoderm is the only inductor required for cranial neural crest cells to differentiate into cartilage. Over 90%...
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