Estrogen receptor beta expression in human vascular tissues.

Bingyi. Han
Estrogens exhibit potent anti-atherogenic effects through mechanisms that may involve direct effects on the artery wall. The existence of the classical estrogen receptor (ERalpha) in vascular tissues has been established. Recently a new estrogen receptor (ERbeta) has been discovered that represents a distinct gene product with homology to the classical ERalpha. The purpose of this thesis was to explore the expression pattern of ERbeta, in normal and diseased arteries. My experimental data demonstrate that ERbeta...
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