Optimization of techniques for cardiac preservation: Phosphorus-31 NMR spectroscopic and functional studies in isolated rat and pig hearts.

Ganghong. Tian
The effects of cardioplegic and reperfusion conditions on energy metabolites and cardiac function were investigated in order to define better conditions for heart preservation (4 or 8 hrs). Myocardial energy metabolites (ATP, PCr and inorganic phosphate), intracellular pH and contractile function were followed using $\sp{31}$P NMR spectroscopy and left intra-ventricular balloon, respectively, during preservation and reperfusion in isolated pig and rat hearts. These hearts were subjected to various conditions of cardioplegia and reperfusion which involved...
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