Nitric oxide and the control of catecholamine secretion in rainbow trout (Oncorhynchus mykiss)

Brian McNeill
The aim of this thesis was to investigate the effects of nitric oxide (NO) on both basal and stimulus-evoked catecholamine secretion in rainbow trout (Oncorhynchus mykiss). Experiments were performed in vivo and in situ using an electrical field stimulation technique. Catecholamine secretion rates in situ were markedly reduced in response to electrical stimulation in the presence of the NO donor sodium nitroprusside (SNP; 5 X 10-3 M). This reduction was through the activation of soluble...
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