Enhancement of neural cell regeneration and survival by altering gap junctional communication following brain injury

Mario Y Morin
The adult brain is particularly susceptible to injury given that it lacks significant regenerative capacity. The presence of rare neural stem and progenitor cells - cells capable of self-renewal and specification to a neuronal or a glial lineage - in specific areas of the adult central nervous system (CNS) offers new hope for therapeutic cell replacement. Our laboratory has previously implicated connexin32 (Cx32) in participating in neural progenitor cell fate determination to an oligodendrocyte lineage...
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