The chromatin remodelling protein SNF2L regulates cell number in the developing brain

Darren John Yip
Mutations in genes encoding chromatin-remodelling proteins, such as the ATRX gene, underlie a number of genetic disorders including X-linked mental retardation syndromes; however knowledge of the role of these proteins in CNS development is limited. In Drosophila, ISWI is essential for development, the protein functions as the ATP-hydrolysing component in several chromatin-remodelling complexes. The two mammalian ISWI orthologs, SNF2H and SNF2L are differentially expressed, suggesting that they possess distinct developmental roles. Prevalent expression of SNF2H...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.