The Effects of Perfluoroalkyl Compounds on In Ovo Toxicity and Hepatic mRNA Expression in the Domestic Chicken (Gallus gallus domesticus)

Jason O'Brien
Perfluoroalkyl compounds (PFCs) are a group of chemical surfactants most notably used in non-stick and stain-resistance applications. Due to their wide-spread use and inherent resistance to degradation, several PFCs have become persistent environmental contaminants. Despite the high concentrations of PFCs reported in wild birds and their eggs, very little is known about the toxicological effects they have on avian species. This thesis investigates the developmental toxicity of PFCs in an avian model species: the domestic...
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