Structural and Functional Analysis of the Cell Division Protein MinDNg: Implications of the C-terminus

Asma Abedin
Gram-negative bacteria such as Escherichia coli and Neisseria gonorrhea undergo symmetric cell division controlled in part by the Min system constituting of MinC, MinD and MinE. MinDNg is a peripheral membrane ATPase that functions by recruiting cell division inhibitor MinCNg to the membrane where it prevents septation. The available crystallographic data of archeal monomeric MinD is not ideal for a dimeric bacterial MinD homolog since there is only 30-40% sequence identity between the two organisms....
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