Hepatitis Delta Virus: Identification of Host Factors Involved in the Viral Life Cycle, and the Investigation of the Evolutionary Relationship Between HDV and Plant Viroids

Dorota Sikora
Hepatitis delta virus (HDV) is the smallest known human RNA pathogen. It requires the human hepatitis B virus (HBV) for virion production and transmission, and is hence closely associated with HBV in natural infections. HDV RNA encodes only two viral proteins - the small and the large delta antigens. Due to its limited coding capacity, HDV needs to exploit host factors to ensure its propagation. However, few human proteins are known to interact with the...
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