A role for nitric oxide in the pathogenesis of necrotizing enterocolitis: Discovery, evaluation and design of a novel prophylactic therapy.

Maria. Di Lorenzo
Necrotizing enterocolitis (NEC) is an acute, self-limiting, inflammatory bowel disease of unclear pathogenesis affecting premature infants. It is the most common acquired surgical emergency in the neonatal period. NEC is characterized by necrosis of the bowel wall and may lead to peritonitis, stricture formation with bowel obstruction and lower gastrointestinal hemorrhage. Approximately 10% of premature babies develop NEC with up to 94% of cases seen in infants born at less than 36 weeks gestation. As...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.