Expression and transient nuclear translocation of protein convertase 1 (PC1) during mouse preimplantation embryonic development

Carly St. Germain
Preimplantation embryos express a number of hormones, neuropeptides and membrane receptors known to derive from proteolytic activation of their precursors by proprotein convertases (PCs). The goal of this study was to determine the pattern of expression of the neuroendocrine protein convertase 1 (PC1) in mouse preimplantation embryos. Previous data have shown that PC1 transcripts are detectable by reverse transcription-polymerase chain reaction in unfertilized and fertilized eggs as well as at all stages of preimplantation embryonic...
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