Emergence of highly antibiotic resistant 'Superbugs' and the implications of antibiotic resistance
Johal Gurniak
Many types of bacteria are now insensitive to antibiotics, the drugs which were designed to kill them; this insensitivity is known as antibiotic resistance (AR). Horizontal gene transfer (HGT) is responsible for widely distributing antibiotic resistance among bacteria. ‘Superbugs’, such as Methicillin-Resistant Staphylococcus aureus (MRSA), are particularly evasive, with resistance to several different antibiotics. The expression of high levels of resistance in these bacteria is due to novel, non-standard, proteins, including Penicillin-Binding Protein 2a (PBP2a),...
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