2,3-Butanediol Production with GRAS Microorganisms – Screening, Cultivation, Optimization and Scale-Up –

Ileana-Maria Jurchescu
The objective of the present PhD thesis was the development of an efficient fermentative process for 2,3-butanediol (2,3-BD) production from wood hydrolysates using non-pathogenic microorganisms. In a first step, suitable non-pathogenic strains from different sources were screened for their potential to produce 2,3-BD and a strain improvement by random mutagenesis (UV light) was attempted. The best results were obtained with Paenibacillus polymyxa ATCC 12321 and Bacillus licheniformis DSM 8785. In the shake flask scale batch...
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