Identification of Host Immune Mechanisms Involved in Enterococcal Infections

Matthias Scheb-Wetzel
Enterococcus faecalis has emerged as the third most common cause of life-threatening bacterial nosocomial infections in the US and in Europe. The knowledge of how enterococci interact with the host immune system is still very limited. The aim of this thesis was to explore the role of so far neglected sentinel cells of the innate immune system like mast cells (MC) and dendritic cells (DC). Also the endothelial barrier represents an important first counterpart with...
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