Lipid mediators detected in COVID-19 patients and healthy controls

Cindy McReynolds, Irene Cortes_Puch, Resmi Ravindran, Imran Khan, Pei-An Betty Shih, Bruce D. Hammock, Jun Yang & Bruce G. Hammock
Polyunsaturated fatty acids are metabolized into regulatory lipids important for initiating inflammatory responses in the event of disease or injury and for signaling the resolution of inflammation and return to homeostasis. The epoxides of linoleic acid (leukotoxins) regulate skin barrier function, perivascular and alveolar permeability and have been associated with poor outcomes in burn patients and in sepsis. It was later reported that blocking metabolism of leukotoxins into the vicinal diols ameliorated the deleterious effects...
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These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
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