Depression is associated with disconnection of neurotransmitter-related nuclei in multiple sclerosis

Matteo Martino, Paola Magioncalda, Mohamed Mounir El Mendili, , , Simona Schiavi, Maria Petracca & Matilde Inglese
Background:Depression is frequently associated with multiple sclerosis (MS). However, the biological background underlying such association is poorly understood.Objective:Investigating the functional connections of neurotransmitter-related brainstem nuclei, along with their relationship with white matter (WM) microstructure, in MS patients with depressive symptomatology (MS-D) and without depressive symptomatology (MS-nD).Methods:Combined resting-state functional magnetic resonance imaging (fMRI) and diffusion-weighted MRI (dMRI) study on 50 MS patients, including 19 MS-D and 31 MS-nD patients, along with 37 healthy controls (HC). Main...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.