Fick principle and exercise pulmonary hemodynamic determinants of the six-minute walk distance in pulmonary hypertension

Phillip Joseph, Rudolf K.F. Oliveira, Roza B. Eslam, , Aaron B. Waxman & David M. Systrom
The six-minute walk test is widely used to assess the severity and prognosis of pulmonary hypertension. However, the pathophysiology underlying a compromised six-minute walk distance is incompletely characterized. The purpose of this study is to evaluate the Fick principle and pulmonary hemodynamic determinants of the six-minute walk distance in patients with suspected pulmonary hypertension. Twenty-nine patients were retrospectively studied and underwent a right heart catheterization for the evaluation of suspected pulmonary hypertension. With the pulmonary...
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