Combination of anti-glycopeptidolipid-core IgA antibody and clinical features for diagnosing potential nontuberculous mycobacterium pulmonary disease in routine practice
Takuya Iwasaki, Fumihiro Yamaguchi, Makoto Hayashi, Hitoshi Kobayashi, Kento Hirata, Kenta Miyo, Chika Kondo, Mamiko Kanzaki, Kazusawa Tei, Takashi Abe, Shunsuke Sakakura, Daisuke Inoue, Yohei Yamazaki, Hidetsugu Tateno, Takuya Yokoe & Yusuke Shikama
Background:The anti-Mycobacterium avium complex (MAC) antibody test measures levels of IgA antibody against the glycopeptidolipid (GPL) core in the bacterial cell walls and is a useful clinical indicator of nontuberculous mycobacterium pulmonary disease (NTM-PD). However, it is not currently possible to diagnose the disease using anti-MAC antibodies alone.Objectives:The study aim was to assess the efficacy of the combination of anti-MAC antibodies and clinical findings for diagnosing potential NTM-PD.Methods:This cross-sectional study included 938 patients tested using...
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