Role of insulin-like growth factor (IGF) signalling pathway in cancers of the head and neck.

Garrett MP Brady
Head and neck squamous cell carcinomas, or oral cancer, is the sixth most common cancer globally and is a significant cause of morbidity and mortality. The incidence of oral cancer is rising annually and though there have been advances inresearch and treatment, there has been no improvement of patient survival rates. Additionally, no specific marker is in routine use to predict the clinical behaviour of oral squamous cell carcinoma (OSCC). In recent years, aberrant expression...
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