Investigation of the Functional Roles of Calcium Channels, Inflammatory Cytokines and Tumour Micro-Environmental Factors in a Human In Vitro Model of Breast Cancer Calcification

Shane O'Grady
Microcalcifications are frequently the sole mammographic indicator of breast cancer with several studies suggesting that their presence may also be indicative of increased tumour grade, HER2 overexpression and poor prognosis. Despite their widespread diagnostic usage, the mechanism by which microcalcifications form and their contribution to tumour progression remain poorly understood. Previously, our lab established an in vitro model using a murine cell line. In order to advance our understanding of these vital diagnostic markers, we...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.