An investigation into the expression, content and function of exosomes in an experimental model of epilepsy

Epilepsy is a serious neurological disease characterised by recurrent unprovoked seizures affecting 65 million people worldwide. Current anti-epileptic therapies target only symptomatic seizures and are not fully effective in ameliorating disease pathophysiology. Temporal lobe epilepsy is the most common form of epilepsy in adults and a third of temporal lobe epilepsy patients are drug refractory, and the underlying pathophysiology remains to be fully elucidated. Recent work revealed microRNAs serve important functions in cells, in post-transcriptional...
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