The Optimisation and Derivative Design of Lead Compounds to Inhibit Staphylococcus aureus Surface Proteins Using Computational Tools

Atopic dermatitis (AD), also known as eczema, is a genetically transmitted chronic skin disorder that is associated with other conditions such as asthma and allergic rhinitis. It affects people at all stages of life and can seriously impair quality of life due to repeated itching and scratching resulting in crusted lesions and sleep loss. Staphylococcus aureus colonisation on the skin of patients with AD exacerbates the symptoms. Current treatments for S. aureus colonised AD skin...
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