Design and Development of Multi-Targeted Metallodrugs as Potential Chemotherapeutic Agents

Reece G. Kenny
Cancer remains a major global health burden despite significant advances in treatmentregimens. Current drug treatments, including those involving platinum drugs, havedrawbacks including dose limiting toxic side effects and either acquired or intrinsicdrug resistance. The development of safer and more effective drug treatments remainsa major research focus. The platinum drugs in clinical use primarily target DNA.Our Group previously developed novel multi-targeted platinum(II) complexes capableof not only binding cancer cell DNA but also possessing the ability to...
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