Non-melanoma skin cancer in HIV infection: the role of human papillomavirus (HPV), individual immunogenotype (HLA ‘tissue type’) and Merkel cell polyomavirus (MCV)

Sacha Imran Goolamali
Non-melanoma skin cancer (NMSC) in HIV presents increasing problems e.g. incidence and morbidity. Ultraviolet light and human papillomavirus (HPV) are implicated in NMSC pathogenesis. In HIV, HPV is unequivocally involved in oral, anogenital and cervical squamous cell cancer (SCC) but its role in cutaneous SCC is unclear. Merkel cell polyomavirus (MCV), the cause of Merkel cell carcinoma, has not been investigated in NMSC in HIV. HLA immunogenotype characterises some dermatoses in HIV and associations with...
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