A systems-based bottom-up mathematical modelling framework for investigating the effect of drugs on solid tumours

Cong Liu
Understanding the effect of drugs on solid tumours presents a number of challenges owing to the complexity of the blood flow and drug transport, as well as the highly complex biochemical networks involved in the cellular response with characteristics of high non-linearity of signal transduction. It is imperative to develop a bottom-up systematic computational framework that is able to disentangle the multiple layers of complexity, to present mechanistic and predictive descriptions of drug effect on...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.