Molecular consequences of SARS-CoV-2 liver tropism

Nicola Wanner, Geoffroy Andrieux & Victor G Puelles
Extrapulmonary manifestations of COVID-19 have gained attention, not only due to their links to clinical outcomes, but also due to their potential long-term sequelae. Recent evidence has shown multi-organ tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including heart, kidney and liver. Previous studies have shown that close to 20% of hospitalized patients with COVID-19 develop liver injury, showing an association to disease severity. Here, we characterized SARS-CoV-2 liver tropism in autopsy samples, based...
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