Low Sensitivity of Pooled Chlamydia Testing in a Sample of the Young German General Population

Karin Haar, Thomas Meyer, Sarika Desai, Michael Thamm, Matthias An Der Heiden, Viviane Bremer & Osamah Hamouda
Objective: To compare sensitivity of pooled urine testing with single specimen testing using NAAT (nucleic acid amplification test). To determine Chlamydia prevalence among adolescents in Germany. Methods: Urine samples from 15-17 year old female and 16-17 year old male participants of a nationwide representative study in children and adolescents sampled between 2003 and 2006 were tested individually and in pools of 4 using BDProbeTec ET System (strand displacement amplification). Specificity, sensitivity, positive and negative predictive...
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