Travel-associated neurological disease terminated in a postmortem diagnosed atypical HSV-1 encephalitis after high-dose steroid therapy – a case report

Andreas Osterman, Viktoria C. Ruf, Christina Domingo, Andreas Nitsche, Peter Eichhorn, Hanna Zimmermann, Klaus Seelos, Sabine Zange, Konstantinos Dimitriadis, Hans-Walter Pfister, Thorsten Thye, Armin Giese, Dennis Tappe & Stephan Böhm
Background Human encephalitis can originate from a variety of different aetiologies, of which infection is the most common one. The diagnostic work-up is specifically challenging in patients with travel history since a broader spectrum of unfamiliar additional infectious agents, e. g. tropical disease pathogens, needs to be considered. Here we present a case of encephalitis of unclear aetiology in a female traveller returning from Africa, who in addition developed an atypical herpes simplex virus (HSV)...
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