Genetic Diversity and Spatial Segregation of Francisella tularensis Subspecies holarctica in Germany

Sandra Appelt, Kristin Köppen, Aleksandar Radonić, Oliver Drechsel, Daniela Jacob, Roland Grunow & Klaus Heuner
Francisella tularensis is an intracellular pleomorphic bacterium and the causative agent of tularemia, a zoonotic disease with a wide host range. Among the F. tularensis subspecies, especially F. tularensis subsp. holarctica is of clinical relevance for European countries. The study presented herein focuses namely on genetic diversity and spatial segregation of F. tularensis subsp. holarctica in Germany, as still limited information is available. The investigation is based on the analysis of 34 F. tularensis subsp....
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