The Role of F420-dependent Enzymes in Mycobacteria

Brendon Lee
Tuberculosis (TB) is the leading cause of death by an infectious disease, recently surpassing HIV/AIDS. The causative agent, Mycobacterium tuberculosis, is difficult to treat as it can survive harsh conditions and can switch between an active infection, which causes ~1.5 million deaths a year, and a latent state, which infects up to one third of the world’s population. M. tuberculosis is also becoming more resistant to frontline drugs, making it a dangerous world epidemic. It...
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