Transcriptional regulation of slc6a19 along the crypt-villus axis

Emrah Tumer
Digestion of proteins takes place mainly in the small intestine followed by the absorption of amino acids and peptides by enterocytes. The absorption surface area in the intestine is drastically increased by finger-like protrusions along the small intestinal lumen (called villi) and invaginations (called crypts). Enterocytes develop from stem cells in the crypt and differentiate into mature enterocytes while moving along the crypt–villus axis. The Slc6a19 mRNA and its resulting B0AT1 protein show a striking...
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