Topical antibiotic use coselects for the carriage of mobile genetic elements conferring resistance to unrelated antimicrobials in Staphylococcus aureus

Glen P. Carter, Mark Schultz, Sarah L. Baines, Anders Gonçalves Da Silva, Helen Heffernan, Audrey Tiong, Peter H. Pham, Ian R. Monk, Timothy P. Stinear, Benjamin P. Howden & Deborah A. Williamson
Topical antibiotics, such as mupirocin and fusidic acid, are commonly used in the prevention and treatment of skin infections, particularly those caused by staphylococci. However, the widespread use of these agents is associated with increased resistance to these agents, potentially limiting their efficacy. Of particular concern is the observation that resistance to topical antibiotics is often associated with multidrug resistance, suggesting that topical antibiotics may play a role in the emergence of multidrug-resistant (MDR) strains....
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.