Finite element results (archive): low RyR density, with mitochondria

David Ladd
Results from a reaction-diffusion finite element model of calcium signalling in a rat ventricular cardiomyocyte. Solved for the first 30 ms of the calcium transient in an 8 sarcomere section.
Calcium is released from RyR clusters with a minimum 1um spacing between them (50 clusters per z-disk). Regions representing mitochondria are excluded to produce barriers to diffusion in the intracellular space.
To view the results of the calcium and fluorescence-bound calcium fields, visualisation of the results in...
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