Effect of ion transport and carbonic anhydrase inhibition on parotid salivary

Alan Beal
In kangaroos, parotid gland secretion has >90% dependence on carbonic anhydrase activity whereas the mandibular gland secretion has >90% dependence on transport of chloride by the triple symport. Unlike kangaroos, parotid salivary [bicarbonate] in wombats is essentially constant over the whole flow range and exceeds [chloride] except at peak flow. Consequently, saliva formation by the wombat parotid gland could be initiated by acinar HCO3 secretion as in the kangaroo parotid followed by substantial ductal exchange...
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