Coral accurately bridges paired-end reads alignment

Q. Shi & M. Shao
Motivation: The established high-throughput RNA-seq technologies usually produce paired-end reads. A challenging problem is therefore to computationally infer the alignment of entire fragments given the alignment of the two mate ends. Solving this problem essentially provide longer RNA-seq reads, and hence benefits downstream RNA-seq analysis. Results: We introduce Coral, a new tool that can accurately bridge paired-end RNA-seq reads. The core of Coral is a novel optimization formulation that can capture the most reliable bridging...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.