Effects of CPAP-respiration on markers of glucose metabolism in patients with obstructive sleep apnoea syndrome: a systematic review and meta-analysis

Lars Hecht, Ralph Möhler & Gabriele Meyer
Background: Obstructive Sleep Apnoea Syndrome (OSAS) is a condition of obstruction, apneas and arousals while sleeping. It has been suggested that OSAS independently influences glucose metabolism. The main treatment for OSAS is continuous positive airways pressure (CPAP). Objectives: To assess the effects of CPAP on insulin resistance and glucose metabolism. Search strategy: We searched Medline, Embase and the Cochrane Controlled Trial Register (January 2010). Selection criteria: We included randomised and non-randomised trials comparing CPAP with...