Effect of aging on esophageal motility in patients with and without GERD

Christian A. Gutschow, Jessica M. Leers, Wolfgang Schröder, Klaus L. Prenzel, Hans Fuchs, Elfriede Bollschweiler, Marc Bludau & Arnulf H. Hölscher
Background/Aims: The impact of aging on esophageal motility is not completely understood. This study aims at assessing 1) whether degeneration of esophageal body motility occurs with age and 2) whether this development is influenced by gastroesophageal reflux disease (GERD). Methods: 326 consecutive patients with symptoms of GERD underwent a diagnostic work-up including a water-perfused esophageal manometry. Patients were divided by age: 17–39 years (group 1, n=75), 40–49 years (group 2, n=79), 50–59 years (group 3,...