Beta-trace protein (prostaglandin D synthase) – a immunological marker as advanced diagnostic for CSF-leaks

Olaf Michel & Gregor Bachmann-Harildstad
Introduction Patients with a CSF leak are at risk: in 40% of patients with a known CSF fistula, Streptococcus pneumoniae or Haemophilus influenzae meningitis occurred. The cumulative risk to develop meningitis exceeded 85% after 10 years in 160 patients with traumatic CSF leaks. The mortality[for full text, please go to the a.m. URL]