Embryonic stem cells release neurotrophins and differentiate along neural pathway after conditioning with brain extracts – „in-vitro Modelling of Stem Cell Behavior after Implantation following Traumatic Brain Injury“

M. Molcanyi, K. Bentz, P. Riess, R. Ernestus, E. Neugebauer, J. Hescheler & U. Schäfer
Objective: Transplantation of embryonic stem (ES) cells was shown to improve the neurologic outcome after traumatic brain injury in animal experiments. To clarify the underlying mechanisms, we established an in-vitro model depicting the behaviour of stem cells after implantation into traumatized brain.[for full text, please go to the a.m. URL]