Effects of deep brain stimulation on gene expression in the sensorimotor cortex and the striatum in a rat model of Parkinson’s disease

B. Grieb, C. Moll, G. Engler, A. Sharott, T. Streichert, M. Westphal, A. Engel & W. Hamel
Objective: Deep brain stimulation (DBS) modulates the expression of immediate early genes and of genes involved in neurotransmission suggesting down-stream molecular alterations. To our knowledge, no experimental work has been published reporting the effect on gene-expression in distinct brain areas[for full text, please go to the a.m. URL]