Accumulation of genetic and epigenetic alterations in glioblastoma during progression

R. Martinez, V. Rohde, G. Schackert & M. Esteller
Objective: Glioblastoma, the most frequent primary brain tumor in adults has an inherent tendency to recur. The molecular basis of the recurrence process in GBM is still poorly understood. We aimed to analyze both genetic and epigenetic alterations occurring in GBM during disease progression. Methods:[for full text, please go to the a.m. URL]