Identification and evaluation of the immunogenic tissue antigens TTR and S100A9 in primary brain tumors by automated two-dimensional protein fractionation

C. Herold-Mende, D. Stoycheva, R. Warta, R. Ahmadi, P. Beckhove & A. Unterberg
Objective: Identification of antigens that trigger pathogenic T-cell responses in tumors and therefore might serve as antigens used for immunotherapy is still a major challenge of basic and translational immunology. Most methods applied so far are either indirect or restricted to selected HLA-I subtypes[for full text, please go to the a.m. URL]