Screening for DNA methylation in brain tumors in children and infants

S. Schlosser, J. Kreth, J. Mühlisch & M. Frühwald
Objective: The role of DNA methylation in epigenetic gene silencing and its usefulness as a clinical marker has been demonstrated over the last years. Our aim was to investigate genome-wide DNA methylation in high risk brain tumors of childhood to identify aberrantly methylated target genes. Methods:[for full text, please go to the a.m. URL]