Impact of differentiation resistance on tumor stem cell phenotype in gliomas

B. Campos, F. Wan, R. Ahmadi, N. Becker, C. Herold-Mende & A. Unterberg
Objective: The so-called brain tumor stem cell concept postulates that immature cell populations reside within a given tumor and seem to be irresponsive to physiological differentiation stimuli, persisting in an undifferentiated state associated with high tumorigenicity and therapy resistance. Such [for full text, please go to the a.m. URL]