Carnosine – a potent inhibitor of growth of human glioblastoma cells in vitro and of HER2/NEU cells in vivo affect cellular function at the level of glycolysis

C. Renner, A. Seyffarth, A. Asperger, N. Zemitzsch, R. Gebhardt, J. Meixensberger & F. Gaunitz
Objective: Up to now, no effective drug or therapy regimen for the treatment of glioblastoma multiforme is available. We investigated whether the dipeptide, carnosine, might be a promising candidate. Methods: For in vitro analyses we used the cell line T98G as well as primary cell cultures established[for full text, please go to the a.m. URL]