Re-resection, Implantation of Carmustine wafers and intensified chemotherapy in the treatment of recurrent glioblastoma: analysis of the impact of aggressive treatment strategies

C. Ewelt, J. Schroeteler, W. Stummer, J. Felsberg, H.-J. Steiger & M. Sabel
Objective: Because the primary treatment of patients with Glioblastoma multiforme (GBM) is the use ofnalkylating drugs (AD), the role of a rechallenge with AD upon recurrence is subject to discussion. In addition, the pivotal role of cytoreductive surgery for GBM, as demonstrated for the primary treatment,[for full text, please go to the a.m. URL]