First experiences with low dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity

M. Seiz, P. Kohlhof, M. Brockmann, P. Vajkoczy, K. Schmieder & J. Tüttenberg
Objective: Gliomatosis cerebri is a rare primary cerebral tumor entity characterized by diffuse infiltrative growth patterns representing a WHO grade III malignancy. The prognosis is dismal and therapeutical options are still controversial. In contrast to other high grade gliomas, angiogenesis is thought[for full text, please go to the a.m. URL]